I find it kind of odd that you can't apply gene changes to puppies at all. I bought a gene change recently and just realized I have to wait for the puppy to grow up to apply it, which is a little annoying. I'm not sure if this is the same case for things like sex swaps either, but I think it'd be a good convenience thing to allow these changes to be made to puppies because I don't really see a reason to make waiting for adulthood necessary.